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☆ Signs of Alzheimer’s were everywhere. Then his brain improved
▼ + stars: | 2024-05-18 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +16 min

Blood biomarkers of telltale signs of early Alzheimer’s disease in the brain of his patient, 55-year-old entrepreneur Simon Nicholls, had all but disappeared in a mere 14 months. “I don’t use the term ‘reverse.’ I don’t know what reverse means when it comes to the field of Alzheimer’s,” Isaacson said. ‘It was time to turn to my brain’Slowly, Nicholls’ heart condition began to improve, but the bad news didn’t end there. A brain scan found telltale signs of vascular damage in Nicholls’ brain, which occurs when the tiniest blood vessels are starved of oxygen. Not only was Nicholls blood negative for amyloid and tau, the test suggested that his brain amyloid might be normal, with no distinguishable signs of the disease.

Persons: Sanjay Gupta, Anderson Cooper ”, Richard Isaacson, Simon Nicholls, “, ”, Isaacson, “ Simon, ” Isaacson, Nicholls, ” Nicholls, Anderson Cooper, It’s, APOE4, Simon, ” Simon Nicholls, Sylver, Lewy, Richard Isaacson ‘, APOE ε4, “ I’ve, Isaacson doesn’t, “ I’m, Shocked, Dr, we’d, “ It’s, Salvadore, Richard Isaacson “, ‘ It’s, I’m Organizations: CNN, telltale, ” CNN, Boca Raton Locations: Boca Raton , Florida, New York City, Florida, Nature, Miami, Isaacson’s Florida, tirzepatide

☆ Ancient DNA reveals genetic roots of multiple sclerosis and other diseases
▼ + stars: | 2024-01-11 | by ( Katie Hunt | ) edition.cnn.com time to read: +8 min

These genetic variants may have subsequently proved beneficial to European populations in making the shift from hunting and gathering to farming. “DNA from hunter-gatherers is present at higher levels in Northeastern Europe, which means the region has an elevated genetic risk of developing Alzheimer’s disease,” Barrie said. Similarly, the ancient genetic information shed light on the evolutionary history of traits such as height and lactose tolerance. And for most traits, MS included, the genetic effects are the result of multiple genetic variants,” he said. “Ultimately, we can’t say that MS came from Bronze Age populations, but these populations’ movements and environments contribute to differences in MS risk today.”

Persons: “, ”, Rasmus Nielsen, It’s, William Barrie, Astrid Iversen, ” Iversen, ε4, ” Barrie, Samira, Asgari, Tony Capra, Capra, wasn’t Organizations: CNN —, University of California, Danish National, University of Cambridge’s, University of Oxford, Icahn School of Medicine, Bakar Computational Health Sciences Institute Locations: Western Europe, Central Asia, Europe, Berkeley, Kazakhstan, Northeastern Europe, Mount Sinai, New York, Bakar, San Francisco

☆ Loss of slow-wave sleep raises dementia risk, study finds
▼ + stars: | 2023-10-30 | by ( Kristen Rogers | ) edition.cnn.com time to read: +6 min

CNN —Loss of slow-wave sleep as you age may increase your risk of developing dementia, according to a new study. Slow-wave sleep is the third stage of sleep, which is important for brain health. Each percentage decrease in slow-wave sleep per year was linked with a 27% increased risk of developing dementia and a 32% higher risk of Alzheimer’s disease dementia. The rate of slow-wave sleep loss accelerated from age 60, peaked from ages 75 to 80 and slowed afterward. “This is an important study yet again showing the impact of quality of sleep on a person’s risk of cognitive decline and dementia,” Isaacson said.

Persons: ”, Matthew P, Pase, “, Richard Isaacson, Isaacson wasn’t, ” Pase, ” Isaacson, it’s, Rudolph Tanzi, Tanzi wasn’t, Pase’s Organizations: CNN, Monash University, Framingham Heart Study, US, Blood Institute, Study, Genetics, Aging Research, Massachusetts General Hospital, ” Locations: Australia, Florida, Framingham, Massachusetts

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